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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-MUT-056399
MUT-056399

Chemical Structure : MUT-056399

CAS No.: 1269055-85-7

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MUT-056399 (FAB-001)

货号: PC-45426Not For Human Use, Lab Use Only.

A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.

规格 价格 库存 数量
10 mg ￥4000 In stock
50 mg ￥12000 In stock
100 mg ￥16800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli; shows activity against S. aureus strains, including MSSA, MRSA, linezolid-resistant, and multidrug-resistant strains with MIC90s of 0.03-0.12 ug/ml; also has active against coagulase-negative staphylococci with MIC90s of 0.12-4 ug/ml; active in vivo (19.3-49.6 mg/kg/day).

Bacterial Infection

Preclinical

物理化学性质&存储条件

分子量 293.2654
分子式 C15H13F2NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 31 mg/mL
Chemical Name/SMILES

Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-

参考文献

1. Escaich S, et al. Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7.

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