ML-264 |CAS:1550008-55-3 Probechem Biochemicals

Chemical Structure : ML-264

CAS No.: 1550008-55-3

加入收藏

ML-264 (ML264;ML 264)

货号: PC-45778Not For Human Use, Lab Use Only.

ML-264 (ML 264) is a potent, selective of KLF5 expression inhibtor, withour effect on kinases associated with the KLF5 pathway.

规格	价格	库存
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ML-264 (ML 264) is a potent, selective of KLF5 expression inhibtor, withour effect on kinases associated with the KLF5 pathway.
ML-264 inhibits the proliferation of DLD-1 cells with IC50 of 29 nM, and several other KLF5-expressing cell types as well HCT116, IC50 560 nM; HT29, IC50=130 nM; SW620, IC50=430 nM).
ML-264 potently inhibits proliferation of colorectal cancer cells in vitro through modifications of the cell-cycle profile.
ML-264 efficiently inhibits growth of the tumo in an established xenograft mouse model of colon cancer.

物理化学性质&存储条件

分子量	384.8777
分子式	C17H21ClN2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Propenamide,3-(3-chlorophenyl)-N-[2-[methyl(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-2-oxoethyl]-,(2E)-

参考文献

1. Bialkowska A, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Ruiz de Sabando A, et al. Mol Cancer Ther. 2016 Jan;15(1):72-83.

ML-264 (ML264;ML 264)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ML-264 (ML264;ML 264)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.