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首页-小分子抑制剂&激动剂-Immunology/Inflammation-IRAK-GS-5718
GS-5718

Chemical Structure : GS-5718

CAS No.: 2408839-73-4

GS-5718 (Edecesertib, GS5718)

货号: PC-22269Not For Human Use, Lab Use Only.

GS-5718 (Edecesertib) is a potent, selective, and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in clinical development for treatment of inflammatory diseases.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GS-5718 (Edecesertib) is a potent, selective, and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor in clinical development for treatment of inflammatory diseases.

物理化学性质&存储条件

分子量 435.46
分子式 C22H22FN7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[[(1R)-1-Cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-3-pyridinecarboxamide

参考文献

1. Patent WO2020014468 A1.

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