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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-BMS 986158
BMS 986158

Chemical Structure : BMS 986158

CAS No.: 1800340-40-2

BMS 986158 (BMS986158)

货号: PC-62270Not For Human Use, Lab Use Only.

BMS-986158 (BMS986158) is a potent and selective BET inhibitor, disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.

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5 mg ¥2280 In stock
10 mg ¥3680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-986158 (BMS986158) is a potent and selective BET inhibitor, disrupts chromatin remodeling and prevents the expression of certain growth-promoting genes, resulting in an inhibition of tumor cell growth.

物理化学性质&存储条件

分子量 495.627
分子式 C30H33N5O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-2-(3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-(phenyl(tetrahydro-2H-pyran-4-yl)methyl)-5H-pyrido[3,2-b]indol-7-yl)propan-2-ol

参考文献

1. Yin M, et al. Nat Commun. 2020 Apr 14;11(1):1833.

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