BMS-204493 |CAS:215030-90-3 Probechem Biochemicals

Chemical Structure : BMS-204493

CAS No.: 215030-90-3

加入收藏

BMS-204493 (BMS 493;BMS204493)

货号: PC-70293Not For Human Use, Lab Use Only.

BMS-204493 (BMS493) is a potent, pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BMS-204493 (BMS493) is a potent, pan-RAR inverse agonist that blocks RARα activity with IC50 of 114 nM.
BMS-204493 (BMS493) prevents the recruitment of transcriptional coactivators to RARs while stabilizing corepressor interactions.
BMS-204493 (BMS493) blocks the ATRA-induced vasorelaxation.

物理化学性质&存储条件

分子量	404.5
分子式	C29H24O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]benzoic acid

参考文献

1. García-Rodríguez J, et al. Bioorg Med Chem. 2014 Feb 15;22(4):1285-302.

2. Das BC, et al. Tetrahedron Lett. 2012 Mar 14;53(11):1316-1318.

3. Wang Y, et al. Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H51-7.

BMS-204493 (BMS 493;BMS204493)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

BMS-204493 (BMS 493;BMS204493)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.