AZD-0156 |CAS:1821428-35-6 Probechem Biochemicals

Chemical Structure : AZD-0156

CAS No.: 1821428-35-6

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AZD-0156 (AZD0156;AZD 0156)

货号: PC-42030Not For Human Use, Lab Use Only.

AZD-0156 (AZD0156, AZD 0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1780	In stock
50 mg	￥2980	In stock
100 mg	￥4880	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

AZD-0156 (AZD0156, AZD 0156) is a potent, highly selective and orally bioavailable ATM kinase inhibitor with IC50 of 0.58 nM.
AZD-0156 exhibits antitumoral activity, both reducing tumor burden and preventing tumors from growing in an immunocompetent allograft mouse model of AML.

物理化学性质&存储条件

分子量	461.556
分子式	C26H31N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 6.2 mg/mL (Need ultrasonic and warming)
Chemical Name/SMILES	2H-Imidazo[4,5-c]quinolin-2-one, 8-[6-[3-(dimethylamino)propoxy]-3-pyridinyl]-1,3-dihydro-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-

参考文献

1. Degorce SL, et al. J Med Chem. 2016 Jul 14;59(13):6281-92.

2. Morgado-Palacin I, et al. Sci Signal. 2016 Sep 13;9(445):ra91.

AZD-0156 (AZD0156;AZD 0156)

生物&药学活性

物理化学性质&存储条件

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AZD-0156 (AZD0156;AZD 0156)

生物&药学活性

物理化学性质&存储条件

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