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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Integrin-ALG1001
ALG1001

Chemical Structure : ALG1001

CAS No.: 1307293-62-4

ALG1001 (Risuteganib;ALG 1001;ALG-1001)

货号: PC-35165Not For Human Use, Lab Use Only.

ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ALG1001 (Risuteganib, ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis; ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina. In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.

Other Indication

Phase 2 Clinical

物理化学性质&存储条件

分子量 637.666
分子式 C22H39N9O11S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-

参考文献

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