AA-861 |CAS:80809-81-0 Probechem Biochemicals

Chemical Structure : AA-861

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AA-861 (Docebenone)

货号: PC-62455Not For Human Use, Lab Use Only.

AA-861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM.

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生物&药学活性

AA-861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM; induces cytotoxic and anti-proliferative effects in 5-LO-positive Capan-2 pancreatic cancer cells; also efficiently inhibits biofilms by preventing the formation of amyloid-like fibers.

Allergy

Discontinued

物理化学性质&存储条件

分子量	326.436
分子式	C21H26O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(12-hydroxydodeca-5,10-diynyl)- 3,5,6-trimethyl-p-benzoquinone

参考文献

1. Romero D, et al. Chem Biol. 2013 Jan 24;20(1):102-10.

2. Yoshimoto T, et al. Biochim Biophys Acta. 1982 Nov 12;713(2):470-3.

3. Fischer AS, et al. Br J Pharmacol. 2010 Oct;161(4):936-49.

AA-861 (Docebenone)

生物&药学活性

物理化学性质&存储条件

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AA-861 (Docebenone)

生物&药学活性

物理化学性质&存储条件

参考文献

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